Weeks 1 & 2: Introduction to the Nervous System
Simple neural circuits, electric signals in cells, resting potential of membranes, Nernst equation.
Weeks 3 - 5: Chemical Signaling
Filtering, spatio-temporal propagation, ion channels, post-snyaptic receptors, neurotransmitters and pathology, analog-to-digital conversion.
Weeks 6 & 7: Models of Conductors
Electrical variables in cells, core conductor model, Derivation of the cable model, time-dependent solutions.
Weeks 8 - 10: Hodgkin – Huxley
Alan Hodgkin and Andrew Huxley, ionic conductances, derivation of Hodgkin-Huxley eq., Insights from Hodgkin-Huxley
Weeks 11 - 12: Numerical Methods
Discrete time solutions, Euler method, bioelectric prosthesis control, Ronge-Kutta method, solving Hodgkin-Huxley.
Weeks 13 - 15: Applications of Bioelectricity
Parkinson’s Disease, epilepsy, drug addiction, targeted muscle reinnervation, optogenetics.