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FutureLearn

Bacterial Genomes II: Accessing and Analysing Microbial Genome Data Using Artemis

Wellcome Genome Campus via FutureLearn

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Overview

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Use computational tools to investigate microbial genomes

Applying increasingly powerful computation to genomics contributes to important medical breakthroughs.

On this course, you will discover the basic principles of microbial bioinformatics analysis, and comparative genomics. Using Artemis, a free genome browser, you will find out how to investigate whole bacterial genomes, and through the analysis of bacterial genes and proteins, you will explore the genomic features of pathogens.

By the end of this course, you will be able to use genomic data to increase your knowledge of microbial genomes.

This course would benefit those interested in learning how to use tools to investigate bacterial genomes, and acquire bioinformatics skills to evaluate the role of microbial genes in disease. Using analytical tools to access and probe genomes, learners will find out how to perform comparative analyses of genes and their protein products.

The course will be of interest to undergraduates, post-graduates, researchers, bioinformaticians, microbiologists, and healthcare professionals. The opportunity to use online computational tools to probe bacterial genomes will also be of interest to teachers and their 16-18-year-old science and computing students.

Bacterial Genomes: From DNA to Protein Function using Bioinformatics is a recommended pre-requisite. Scientific terminology is explained.

This course will give you an opportunity to learn about and use Artemis, a free genome browser and annotation tool. To run this software effectively, you will require a computer (Windows, Mac or Linux) with 2GB RAM. The current version of Artemis requires version 1.11 of Java to run successfully. Java can be downloaded from this link.

Syllabus

  • Welcome, Reference genomes and introduction to Artemis
    • Welcome to the Course
    • Reference genomes: Genome assemblies, construction, representation, and reliability
    • The bacterial genome browser Artemis
  • Genome annotation, GC (guanine-cytosine) content, and data access
    • Genome Annotation
    • Genomic regions have different content of Gs and Cs
    • Data access
  • Consolidation and Peer Review Project
    • Artemis further practice
    • A real case study where Artemis saves the day!
    • Assignment completion, sharing learning, and peer review
    • Project resolution, Week 3 and the Course Summary
    • Assessment, discussion, reflection and acknowledgments
    • Acknowledgements

Taught by

Dr. Anna Protasio

Reviews

4.9 rating, based on 23 Class Central reviews

4.6 rating at FutureLearn based on 67 ratings

Start your review of Bacterial Genomes II: Accessing and Analysing Microbial Genome Data Using Artemis

  • Profile image for Kaviya Sankar
    Kaviya Sankar
    On this course, you will discover the basic principles of microbial bioinformatics analysis, and comparative genomics. Using Artemis, a free genome browser, you will find out how to investigate whole bacterial genomes, and through the analysis of bacterial genes and proteins, you will explore the genomic features of pathogens.

  • Profile image for Umm-e Khair
    Umm-e Khair
    I had never heard of Artemis before the course but at the end I was very happy with what I had learnt.Wonderful course materials and project. Very interactive and informative.
  • Profile image for Oladeji Sofoluke
    Oladeji Sofoluke
    The course made microbial bioinformatics using a web browser a piece of cake! With guidance in the use of the designated web browser Artemis, I was taught how to identify the probable role of essential genes in the sequenced genome of a bacterial organism through the gene features. Now I can predict with confidence a pathogenicity island in a genome through its GC% content and start & stop codon feature amongst others. It is a course worth the time.
  • Christian Arenas Daza
    Good for anyone who is interested in microbiology and is looking to further develop their skills. It is extremely useful since with the advance of technology one need to keep up. Their videos are very clean and useful to help you navigate through ARTEMIS. However, I do recommend to do the Bacterial genome: from DNA to protein function using bioinformatics as it builds the foundation, although is not a requirement.
  • Nawel Zaatout
    The course was clear, the teachers were great, ive learnt a lot about the software Artemis, i wish everyone can take this course, many thanks.

    Best wishes,
    Nawel
  • Noah Joseph Santos
    thanks great course help me lots I would like to thank everyone for helping me with this stay safe. thank youuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuu
  • Kalema James
    With home lockdown due to the COVID19 pandemic, I chose to gain this new skill of Accessing and analysing microbial genome data with a genome browser Artemis. It's been an awesome experience learning this course that has infinite applications in Medicine and research. Surely I can now investigate bacterial genomes like I have been doing so for a while!
  • Anonymous
    - Great introduction, especially for people who don't have a background in any kind of computing or bioinformatics
    - Mixture of teaching styles e.g. videos, articles... keep course interesting.
    - Plenty of opportunities to practice the skills you learn.
    - Mini projects, quizzes and tasks to test what you've learnt
  • Taking part in Bacterial Genomes: Accessing and Analysing Microbial Genome Data was a great learning experience. I learned a plethora of interesting things about bioinformatics and the course helped understand the field. It was very interesting and maybe I will divi into the topic.
  • Anonymous
    This course is very good for those who want to learn about Artemis and study genomics. The couse instructors are explaining the things in a very easy method. Step by step learning can make the learner take up other tools and softwares of bioinformatics since it can help alot.
  • Anonymous
    The course was centered on bacteria genomics and comparative genomics using Artemis, the EMBL and NCBI. great video aids and highly lucid way of describing complex subject matter like bioinformatics. Easy to follow regardless of your level of bioinformatics skills.
  • Profile image for Hafeez Toluwalope Akinniyi
    Hafeez Toluwalope Akinniyi
    The course is really great! Well planned and detailed. It helped me to understand visualization and annotation of genome sequences using Artemis (among many other things). My journey into bioinformatics looks smoother after completing this country. I'm excited!
  • Anonymous
    I feel like I've learnt lots on this curse and been able to apply what I've learnt in the activities set as part of the course. Also, there are clear instructions and video guides help to explain how to use the software that you download as part of the course.
  • Anonymous
    I really enjoyed this course. This is a great course you must not miss.
    Artemis is an important tool in visualizing a genome. It is a powerful tool in bioinformatics. If you want to increase your knowledge in bioinformatics then you have to take this course.
  • Anonymous
    This is very interesting course for people who interested in learning bioinformatic basics and to improve further. Either for bacterial or eukaryotic research, I suggest to take the course who is new to research and interested in bioinformatics.
  • Ayodele Ayeni
    A very great course to learn about bacterial genomes, annotations, importance of G+C contents, pathogenicity islands, pseudogenes, and using Artemis to analyze all these information for useful purposes and applications.
  • Samira Abaker Hassan
    I need to study well to complete the course to being other courses of medical laboratory course and lam from Sudan and needed more course to learning because being worked so soon done
  • Anonymous
    The course was quite helpful. It has opened my eyes further into the world of bioinformatics. The knowledge obtained shall be applied judiciously. Thank you for the opportunity to learn.
  • Anonymous
    I had never heard of Artemis before the course but at the end I was very happy with what I had learnt.Wonderful course materials and project. Very interactive and informative.
  • Anonymous
    I had never heard of Artemis before the course but at the end I was very happy with what I had learnt.Wonderful course materials and project. Very interactive and informative.

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