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Biostatistics and Design of experiments

Indian Institute of Technology Madras via NPTEL

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Overview

Biostatistics is the application of statistics to different topics in biology including medicine, pharmacy, public health science, agriculture and fishery. It involves the analysis of data from experiments; its interpretation and drawing conclusion from the results. It is very relevant to all UG and PG level degree programmes majoring in Biotechnology and allied fields as well as practicing scientists. It involves the application of statistical theory to real-world problems, the practice of designing and conducting biomedical experiments and clinical trials. Design of experiments is planning experimental strategy, screening a large number of parameters and selecting the important ones, determining the minimum number of experiments and deciding on the mode and manner in which experiment have to be conducted. The course encompasses topics such as distribution of data, sample size, tests of significance, data reduction, regression analysis, comparison of performance of drugs in clinical trials, design of experiments, screening and second order designs. 

Syllabus

Module 1
Introduction to statistics (various distributions)
Normal distribution
Sample and population
Sample and population

Module 2
Z distribution
Z distribution/confidence interval
Tests of significance – t test
Tests of significance – t test

Module 3
Tests of significance – t test
Tests of significance – t test
Tests of significance – t test
Tests of significance – t test

Module 4
F test
ANOVA

Module 5
2 test/Odds ratio
Non parametric tests
Other tests

Module 6
Design of experiment- introduction
Design of experiment
Screening designs
Screening design - Data analysis

Module 7
Screening design - Data analysis
Higher order designs
Higher order designs
Higher order designs

Module 8
Regression analysis
Regression analysis
Data reduction
Data reduction

Taught by

Mukesh Doble

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