David Chen completed this course, spending 5 hours a week on it and found the course difficulty to be hard.
I took the first iteration of this course on Stanford Online (laguinta/edX platform, which is no longer available). It consisted of 6 units, with the first being a refresher. The instructor was a Stanford doctoral candidate, who was incredibly knowledgeable about the subject and explained the concept very clearly. The course was very fast-paced; I found it challenging despite having taken a MATLAB-based course in graduate school in-person. However, the materials covered were thorough -- you get a deep delve into advanced application of MATLAB cell arrays, for example. I also appreciated the course covering some advanced topics on debugging that are critical to robust programming. Overall, I highly recommend this course.