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Indian Institute of Technology, Kharagpur

Aspects Of Biochemical Engineering

Indian Institute of Technology, Kharagpur and NPTEL via Swayam

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Biochemical Reaction Engineering is mostly deals with the most complicated life systems as compared to Chemical Reaction Engineering. To describe the behavior of any life system in terms of mathematical form is the basic essence of biochemical reaction engineering. The present course in true sense is an interdisciplinary subject since biologist, physicist, chemist, technologist and mathematician all join hand in hand to develop realistic models. This specialized subject comprises of transport processes, sophisticated advanced control system besides conventional biology, physics and mathematics. Production of biomolecules can be done broadly in two different ways namely, using enzymes and microbial cells. The present course is designed to cater all the above aspects of the subject. Students undergoing this course will be initially able to differentiate between conventional chemical reaction engineering and biochemical reaction engineering. They also develop the expertise to do the design of any biochemical process which will be very much useful for the industries.INTENDED AUDIENCE:BiotechnologyChemical EngineeringBiochemical EngineeringEnvironmental EngineeringBiochemistryPRE-REQUISITES:Mathematics in 10+2INDUSTRY SUPPORT :IFB Agro Industry; IOC; ONGCDr. Reddy’s LaboratoriesBioconUnited BeveragesRanbaxy Lab. Ltd.Phizer India.


Week 1: Microbiology, Biochemistry and BioproductsWeek 2: Stoichiometry and Thermodynamics of biochemical reactionsWeek 3: Kinetics of homogeneous chemical reactionsWeek 4: Different types of bioreactors and reactor analysisWeek 5: Kinetics of enzyme catalyzed reactions using free enzymesWeek 6: Kinetics of enzyme catalyzed reactions using immobilized enzymesWeek 7: Kinetics of substrate utilization, product formation and biomass production of microbial cellsWeek 8: Kinetics of substrate utilization, product formation and biomass production of microbial cellsWeek 9: Design and analysis of activated sludge process and anaerobic digester. Scale up of bioreactorWeek 10:Transport phenomenon in bioprocessWeek 11:Air and medium sterilizationWeek 12:Operation and Process control, Downstream processing, Economic analysis of biochemical processes and summary & conclusion

Taught by

Debabrata Das



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