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Indian Institute of Technology, Kharagpur

Biological Inorganic Chemistry

Indian Institute of Technology, Kharagpur and NPTEL via Swayam


The extraordinary important role of metal ions in biology, heath, diseases and medicine has become increasingly evident over the last three decades or more. The inorganic aspects of life processes and biological processes can be understood from the viewpoint of the coordination chemistry of metal ions. The study of metal ions in biological systems can only be appreciated from a multidisciplinary approach. It stays within the rapidly growing interface between inorganic chemistry and the living world. It is increasingly recognized that selected metal ions are involved in cellular and subcellular functions.INTENDED AUDIENCE : MSc, MTech and MPharmPREREQUISITES : 1. Coordination Chemistry 2. Basic Bioinorganic ChemistryINDUSTRY SUPPORT : 1. BioTech companies 2. BioProcess companies 3. BioCatalyst industries


Week 1:Outline of metal ions in biology Week 2:Natural and biological ligands for essential metal ions
Week 3:Physical methods to study metal ions biological systems Week 4:Assimilation pathways, transport, storage and homeostasis of biogenic metal ions Week 5:Ion channels and pumps involving sodium and potassium ions Week 6:Magnesium ions for phosphate metabolism and cellular signaling using calcium ions Week 7:Iron ions in life processes: dioxygen management Week 8:Biochemistry of copper ions
Week 9:Enzymes containing zinc ions: Action of Lewis acid Week 10:Biological actions of manganese, cobalt and nickel ions Week 11:Nonmetallic species in biology Week 12:Metal ions in brain and medicine

Taught by

Prof. Debashis Ray

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