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NPTEL

Cell and Molecular Biology

NPTEL via Swayam

Overview

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ABOUT THE COURSE:An individual cell play crucial role in the biological activity of the organ. The coordinated action of different cells present within organ or different organ decide the final outcome in the organism. Biological processes are controlled by different types of molecules such as cell signaling, replication, transcription, protein expression and development. Understanding cellular structure, functions and co-ordination mechanism is important for understanding disease mechanism and designing therapeutic molecules. Apart from these aspects, molecular cell biology theory leads to the development of several diagnostic methods and recombinant DNA technology. The aim of this core course is to provide a detailed insight into the concepts of molecular biology and its mechanisms that control cell functions along with a sense of its complex regulatory mechanisms.INTENDED AUDIENCE: Under graduate and post graduate studentsINDUSTRY SUPPORT: Biocon https://www.biocon.com/Jubilant Life Sciences www.jubl.com/Shantha Biotechnics LtdPanacea BiotecSerum institute of india

Syllabus

Week 1: Origin of Life and Evolution
  • Origin of Life
  • Evolution (Part 1)
  • Evolution (Part 2)
Week 2:Cellular Structure
  • Structure of Prokaryotic Cell
  • Structure of Eukaryotic Cell
  • Cellular Fractionation
Week 3:Cellular Homeostasis
  • Cell Growth and regulation.
  • Mitosis and Meiosis
  • Apoptosis and Autophagy
Week 4:Cellular Transport
  • Transport in Prokaryotic Cells
  • Transport in Eukaryotic Cells (Part 1)
  • Transport in Eukaryotic Cells (Part 2)
Week 5:Cellular Communications
  • Cellular Communication (Part 1)
  • Cellular Communication (Part 2)
  • Cellular Communication (Part 3)
Week 6:Genetic Materials in cells
  • Organization of Prokaryotic Genome
  • Organization of EukaryoticGenome
  • Genome Damage and repair Mechanism
Week 7:Concepts of Genetics (Part 1)
  • Law of Inheritance (Part 1)
  • Law of Inheritance (Part 2)
  • Epigenetics
Week 8:Concepts of Genetics (Part 2)
  • Genetic Recombination
  • Transgenic Organisms
  • Gene regulation in Organism
Week 9:Central Dogma of Molecular Biology (Part 1)
  • Central Dogma of Molecular Biology
  • Structure of DNA
  • Structure of RNA
Week 10:Central Dogma of Molecular Biology (Part 1)
  • Replication
  • Transcription
  • Translation
Week 11:Molecular Immunology
  • Components of Immunology
  • Antibody: Structure, Genetic Diversity and function
  • Vaccines
Week 12:Summary and Conclusions
  • Cell Factory: Concept and applications.
  • Gene Therapy
  • Summary and Conclusions

Taught by

Prof. Vishal Trivedi

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