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Human Genetics

CEC and University of Mysore via Swayam


The study of human genetics can be intellectually fascinating, but it also has plenty of practical applications. From the use of DNA in court cases to the discovery of new therapies for genetic diseases, a thorough understanding of the human genome can have important medical, social and legal impacts. Understanding the genetic basis behind human disease is one of the most important reasons for studying the human genome. While many genetic disorders are not treatable, early diagnosis can help improve the quality of life or even extend the lifespan of sufferers.Current clinical trials on genetic therapies offer the promise of eventual treatments that may give sufferers a life free of symptoms. Diagnostic tests can help couples decide whether to risk passing on specific disease-related genes to their children. Tests assist in vitro fertility doctors to specifically select embryos that do not carry the dangerous gene.



Weekly Lecture Topics


Week 1

Episode 1

1 Introduction

Episode 2

2 Dermatoglyphics 1

Episode 3

3 Dermatoglyphics 2

Week 2

Episode 4

4. Pedigree analysis 1

Episode 5

5. Pedigree Analysis 2

Episode 6

6 Chromosomes

Week 3

Episode 7

7. Heterochromatin

Episode 8

8. Ultrastructure of Chromosome

Episode 9

9. Human Karyotype

Episode 10

10 Banding techniques

Week 4

Episode 11

11. Euploidy and monoploidy

Episode 12

12. Haploidy and polyploidy

Episode 13

13. Anueploidy and nondisjunction

Episode 14

14. Deletions with examples

Week 5

Episode 15

15. Duplications with examples

Episode 16

16. Inversions with examples

Episode 17

17. Translocations with examples

Episode 18

18. Evolutionary significance of Chromosomal aberrations

Week 6

Episode 19

21 Genetic disease and inheritance pattern

Episode 20

22.a)Autosomal dominant inheritance

Episode 21

22.b)Autosomal recessive inheritance

Week 7

Episode 22

23. X- and Y-linked inheritance

Episode 23

24. Multifactorial & mito diseases

Episode 24

25. Oncogenetics

Week 8

Episode 25

26.Tumour suppressor genes

Episode 26

27.Cells of immune system

Episode 27

28. Genetics of immune system

Week 9

Episode 28

29. Innate adaptive immunity & I response

Episode 29

30. Inherited Immunodeficiency

Episode 30

31.a) HGPs i.e. Human Genome Projects

Episode 31

31.b) HGPs i.e. Human Genome Projects

Week 10

Episode 32

32.Genetic markers-SNPs and applications

Episode 33

33. Genetic markers-CNVs and InDels and their implications

Episode 34

34. Prenatal diagnosis- Non-invasive methods

Episode 35

35. Prenatal diagnosis- Invasive method

Week 11

Episode 36

36. Technology in reproductive assistance

Episode 37

37. Gene therapy with reference to hemophilia

Episode 38

38.Cord blood banking and stem cell therapy

Week 12

Episode 39

39.Genetic counseling

Episode 40

40. Eugenics- positive and negative implications

Taught by

Prof. N. B. Ramachandra



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