The course “Immunology”
is a Discipline Specific Elective Course in B.Sc. Zoology under the Choice Based Credit System (CBSE). The course is specially designed to supplement and enhance the understanding of students about different dimensions of Immunology starting from defense systems of the body, immunity, antigens, antibodies, hypersensitivity, cytokines, complement system, vaccines and how our body continuously defends us from various pathogens and maintains homeostasis against many environmental challenges.The objectives of this course are to give the target students/audience an understanding of:
- Fundamentals of the immunology and how our body responds to different environmental challenges.
- Early theories of Immunology, Cells , organs and molecules of the Immune system.
- Different types of immunity (innate and adaptive) employed by the immune system to defend us from foreign pathogenic attacks.
- Organization and functioning of the immune organs, cells and molecules like antibodies, cytokines and chemokines.
- Structure and functions of different classes of immunoglobulins, Antigen-antibody interactions
- Immune dysfunctions (Rheumatoid Arthritis and AIDS)
- Immunoassays (ELISA, RIA, immunoblotting and Hybridoma technology) Monoclonal antibodies in therapeutics and diagnosis
- Hypersensitivity and complement system Vaccines and their developmen
COURSE LAYOUT WEEK 11 Historical Perspective of Immunology2 Early Theories of Immunology3 Cells of the Immune System4 Organs of the Immune System
WEEK 2 5 Anatomical barriers of Immune system6 Inflammation7 Cells and Molecules of Innate Immunity8 Cell Mediated and Humoral ImmunityWEEK 39 Passive and active Immunity (Artificial and Natural)10 Immune Dysfunction (Rheumatoid Arthritis and AIDS)11 HIV-AIDS a Global Health Emergency12 Antigenicity and ImmunogenicityWEEK 413 Immunogens (Factors influencing immunogenicity)14 Adjuvants and Haptens15 Types of Antigens16 B and T-cell EpitopesWEEK 517. Types of Immunoglobulin’s18. Antigen antibody interactions19 Immunoassays20 Hybridoma TechnologyWEEK 621 Monoclonal Antibodies in Therapeutics and Diagnostics22 ELISA, RIA and Immunofluorescence23 Alexa floure tagging of antibodies and Flow cytometry 24 Structure and function of MHC MoleculesWEEK 725 Endogenous and Exogenous pathways26 Antigen Presenting cells27 Antigen processing28 Antigen presentationWEEK 829 B Cell and T cell Signalling in antigen presentation30 Costimulation and reverse costimulation in presentation31 Cytokines and their types32 Properties and Functions of cytokinesWEEK 933 Therapeutic cytokines34 Chemokines and cytokines in infectious diseases 35 Complement System and its components36 Pathways of Complement systemWEEK 10 37 Hypersensitivity and Allergy38 Gell and Coombs classification of Hypersensitivity39 Aeroallergens and their control40 Various types of hypersensitivitiesWEEK 1141 Vaccines and their properties42 Live Vaccines43 Attenuated and Heat killed Vaccines44 DPT, Influenza and Polio vaccines