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Indian Institute of Technology, Kharagpur

Industrial Biotechnology

Indian Institute of Technology, Kharagpur and NPTEL via Swayam

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Overview

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The course aims to provide fundamental insights to exploit enzymes and microbes for the manufacturing of products which have a huge industrial significance. It uniquely blends the science and engineering with various biochemical processes to obtain products of diverse fields such as chemicals, food, bioenergy etc. The course introduces bioreactors, its types, operation methods and provides an experimental demonstration of the same. Strategies to obtain higher yields, design of the reactors and production of biofuels from microbes are thoroughly explained. Students of various disciplines such as biotechnology, chemical engineering, food engineering, and pharmaceutical industries can be benefitted from the course as it discusses the existing bioprocess applications such as wine and cheese making, antibiotics and vaccines etc. The course majorly focusses on the applications and allows students to gain practical knowledge rather than mere theory. Major bottlenecks for the operation of biochemical industries will be discussed.INTENDED AUDIENCE:Biotechnology Chemical Engineering Biochemical Engineering Food Technology Environmental Engineering Applied Microbiology Pharmacy.PRE-REQUISITES: Knowledge in microbiology Biochemistry and mathematics in 10+2 levelINDUSTRY SUPPORT: LIST OF COMPANIES/INDUSTRY THAT WILL RECOGNIZE/VALUE THIS ONLINE COURSE DuPont India IFB Agra Industry IOC; ONGC Dr. Reddy’s Laboratories Biocon United beverages.

Syllabus

Week 1: Introduction, Microbes and enzymes of industrial importanceWeek 2: Different types of bioreactors and bioreactor design
Week 3: Microbial growth, substrate degradation and product formation kinetics, Tutorial 1
Week 4: Instrumentation, Sterilization of air, media and reactor
Week 5: Upstream and Downstream processing
Week 6: Production of Oxy Chemicals I: Tax and non-tax alcohol, Brewing industry, Tutorial 2Week 7: Production of Oxy Chemicals II: Wine making, Vinegar and citric acid production, Tutorial 3
Week 8: Production of Oxy Chemicals III: Antibiotics: Penicillin; Streptomycin
Week 9: High fructose corn syrup, Cheese making, and Single cell production
Week 10: Vaccines production and Metal leaching
Week 11: Bioenergy- Gaseous fuels: Biohydrogen, Biomethane and Microbial fuel cell; Liquid fuels: Bioethanol, Biodiesel and BiobutanolWeek 12: Aerobic and Anaerobic wastewater treatment processes,Tutorial 4

Taught by

Prof. Debabrata Das

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