Symmetry, point groups and space groups, crystal lattices. Scattering, diffraction, reciprocal lattice. powder diffraction. Single crystal methods. Data collection and processing synchrotron radiation, phase problem in crystallography. Patterson and direct methods, Rietveld refinement, intermolecular interactions electron density analysis. Basics of neutron diffraction, electron diffraction.
INTENDED AUDIENCE: Research students, Scientists from Pharmaceutical and materials industry and teachers(faculty) at Universities
PREREQUISITES: Basic mathematics
Week 1 : Basics of symmetry ,2 Point groups Week 2 : Space groups, Equivale3nt points, Wycoff notation. Week 3 : Basics of diffraction, Laue’s conditions and Bragg’s Law Week 4 : Translational symmetry elements, glide plane, screw axis, relevance of symmetries. Week 5 : Phase problem Week 6 : Patterson Synthesis Week 7 : Direct methods Week 8 : Single crystal and powder XRD Week 9 : Refinement protocols Week 10 : Bond lengths, angles and conformation Week 11 : Intermolecular interactions Week 12 : Applications in Pharmaceutical and materials industry