Natural Medicinal Chemistry

Overview

Natural Medicinal Chemistry is a core compulsory course for pharmacy majors. It is highly theoretical and practical, closely related to courses such as Organic Chemistry, Analytical Chemistry, and Spectral Analysis. This course provides foundational knowledge for the research and development of traditional Chinese medicine and natural medicines. The course introduces the structural characteristics, physical and chemical properties, and methods of extraction, separation, and purification of natural medicinal compounds, mainly focusing on biological activities or bioactive components. The course will be taught entirely online in English, incorporating examples of Chinese herbal medicines, natural medicines, and marine drugs from Guangxi and ASEAN regions.

Syllabus

Chapter 1 General Introduction of Natural Medicinal Chemistry

1.1 Overview of Natural Medicinal Chemistry
1.2 Development of Natural Medicinal Chemistry
1.3 Extraction and isolation Methods – Part one
1.4 Extraction and isolation Methods – Part two
1.5 Structure Identification of Natural Products
1.6 Syntheses of Natural Products

Chapter 2 Saccharides and Glycosides

2.1 Saccharides
2.2 Glycosides
2.3 Cleavage of Glycosidic Bonds

Chapter 3 Phenylpropanoids

3.1 Introduction of Phenylpropanoids
3.2 Coumarins
3.3 Physicochemical Properties of Coumarins
3.4 Extraction and Isolation of Coumarins

Chapter 4 Quinones

4.1 Introduction of Quinones
4.2 Physical Properties of Quinones
4.3 Acidity of Quinones

Chapter 5 Flavonoids

5.1 Introduction of Flavonoids
5.2 Acidity and Basicity of Flavonoids
5.3 Anthocyanidins

Chapter 6 Terpenoids and Volatile Oils

6.1 Introduction of Terpenoids
6.2 Diterpenoids
6.3 Volatile Oils

Chapter 7 Triterpenoids and Their Glycosides

7.1 Tetracyclic Triterpenoids
7.2 Ginsenosides

Chapter 8 Steroids and Their Glycosides

8.1 Cardiac Glycosides
8.2 Steroidal Saponins

Chapter 9 Alkaloids

9.1 Overview of Alkaloids
9.2 Naming Principles, Classification, Physicochemical and Biological Properties of Alkaloids

Chapter 10 Marine Drugs

10.1 Overview of Marine Drugs
10.2 Structure Types and Classification of Marine Drugs

Chapter 11 Research and Development of Natural Medicines

11.1 Ways to Develop New Drugs from Natural Medicines or Traditional Chinese Medicines
11.2 Research Methods for Bioactive Components in Natural Medicines