Expanding Proteomic Horizons with Single-Molecule Proteome and Proteoform Analysis

Join a 59-minute webinar featuring renowned proteomics experts Dr. Parag Mallick and Dr. Andreas Hühmer as they explore revolutionary advances in single-molecule protein analysis. Discover how the Protein Identification by Short-epitope Mapping (PrISM) approach enables comprehensive proteome coverage and proteoform analysis with unprecedented sensitivity and reproducibility. Learn about novel biochemistry techniques for single, intact protein molecule immobilization, cutting-edge instrumentation for affinity-reagent probing, and machine learning applications in data interpretation. Explore how multi-affinity probes binding short epitopes can identify over 95% of the human proteome using just 300 probes. Gain insights into quantifying proteoform abundance, including highly modified proteins like tau, using standard commercially available affinity reagents. Master the fundamentals of single-molecule protein analysis and understand its potential impact on biological research and human health through practical demonstrations and performance data from this emerging proteomics platform.