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YouTube

Exploring Membrane Proteins: Strategies for Research and Applications

Labroots via YouTube

Overview

Join a 44-minute webinar featuring experts Suzanne Smith and Dr. Kallol Gupta as they delve into membrane protein research strategies and applications. Learn essential approaches for membrane protein expression, extraction, and stabilization, including considerations for optimizing sample yield and integrity. Discover how different polymers like SMALPS can be used for specific membrane protein solubilization based on lipid bilayer interactions. Explore cutting-edge techniques for capturing membrane proteins in their native membrane nanodomain contexts, including a high-throughput analysis platform using membrane-active polymers (MAP) that enables near-complete extraction of target membrane proteins while maintaining their local membrane environment. Gain insights into the comprehensive database quantifying polymer-specific extraction variability for over 2,000 unique mammalian membrane proteins and learn about applications across various organellar membranes including the endoplasmic reticulum, mitochondria, lysosome, Golgi, and autophagosome.

Syllabus

Fall into Proteomics webinar series, Day 3 - Exploring membrane proteins

Taught by

Labroots

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