Is This the Beginning of the End of Lupus? Everything You Need to Know About CAR-T Therapy

This 10-minute video from Connected Rheumatology explores whether CAR-T therapy represents a revolutionary breakthrough for lupus treatment. Discover how this targeted immune therapy works by re-engineering patients' T cells to eliminate harmful auto-reactive B cells that produce damaging antibodies in lupus. Learn about the fundamental mechanisms of autoimmunity, the current state of CAR-T clinical trials, and the promising early results showing significant improvements in severely ill patients. Understand both the benefits and risks of this cutting-edge treatment, including potential infection risks, inflammatory responses, and cost barriers. The video also examines why autoimmunity occurs in the first place and how bioengineering advancements might bring long-lasting remission to lupus patients. Includes time-stamped sections covering autoimmunity basics, CAR-T therapy explanation, current research status, and future prospects for this potentially transformative treatment approach.