Fine-mapping Complex Traits in Biobanks - MPG Primer (2025)

This 45-minute lecture from the Medical and Population Genetics Primer series explores fine-mapping techniques for complex traits in biobanks, presented by Masahiro Kanai from the Broad Institute and Massachusetts General Hospital on April 3, 2025. Learn about the fundamental approaches to identifying causal genetic variants underlying complex traits using biobank-scale data. Part of the Broad Institute's educational initiative, this session provides an accessible introduction to complex trait genetics concepts, including human genetic variation, genotyping, DNA sequencing methods, statistical approaches, and data analysis techniques. Designed for a diverse audience ranging from research technicians to established investigators entering the field, this presentation delivers valuable insights into the specialized field of medical and population genetics.