Radioactive Iodine Uptake and Ablation - Thyroid Treatment Mechanisms

This 35-minute educational video explores the comprehensive details of Radioactive Iodine Uptake (RAIU) and Radioactive Iodine Ablation (RAIA) procedures used in thyroid disorders. Delve into thyroid gland anatomy including follicles, follicular cells, and parafollicular cells, while understanding the biochemistry of thyroid hormones such as thyroglobulin, calcitonin, triiodothyronine (T3), and tetraiodothyronine (T4). Learn about iodine metabolism processes including oxidation, organification, coupling, and the role of thyroperoxidase in hormone synthesis. Examine the physics of radioactive tracers, fractional uptake measurements, and different radiation types (alpha, beta, gamma) used in diagnostic and therapeutic procedures. Discover clinical applications for conditions like Graves' disease, toxic multinodular goiter, thyroid cancer, thyroiditis, and thyrotoxicosis, along with special considerations for pregnancy and lactation. The video also covers thyroid antibodies and levothyroxine therapy as part of comprehensive thyroid disease management.