Tissue Hypoxia - Types of Hypoxia (Hypoxic, Ischemic, Anemic, Cytotoxic) - Pathophysiology

Explore a comprehensive 34-minute medical video that delves into the pathophysiology of tissue hypoxia and its four main types: hypoxic, ischemic, anemic, and cytotoxic hypoxia. Learn about the mechanisms of cell injury and death, distinguishing between reversible and irreversible cellular changes due to oxygen deprivation. Understand key concepts including hypoxemia, cyanosis, oxygen saturation measurements (SaO2, SpO2, PaO2), A-a gradient, and the pathological processes involving free radicals and reactive oxygen species. The lecture covers clinical manifestations of hypoxia in various organ systems, explaining conditions like angina, infarction (both pale and red), ischemia, shock, and vascular occlusions from thrombi and emboli. Perfect for medical students and healthcare professionals seeking to understand the fundamental mechanisms of tissue oxygen deprivation and its clinical significance.