This course deals with the algorithms employed by mapping and genome assembly programs commonly used. It was only after completing the course that I realised that the course instructor, Ben Langmead, is actually the first author of the bowtie paper which is one of the most commonly used programs for DNA mapping. The lecture material is extremely well explained and accessible both to students with a computational background and to biologists. The algorithms employed are much better explained than in some other bioinformatics courses on Coursera that deal with some similar topic (UCSD Specialisation, etc) as the course specifically deals with the algorithms rather than teaching bioinformatics in general (though I find the other courses quite good too). The Practical courses are extremely useful, and help a great deal to understand how the algorithms described during the lectures can be easily applied in an accessible programming language. The Practicals are carried out in Python. Prior knowledge of Python is definitely a very big plus to getting the most out of this course, but not essential to understanding. I really recommend this course and really hope to see more courses from the same instructor in the future!