OpenFold - Lessons and Insights From Rebuilding and Retraining AlphaFold2

OpenFold - Lessons and Insights From Rebuilding and Retraining AlphaFold2

Institute for Pure & Applied Mathematics (IPAM) via YouTube Direct link

Intro

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1 of 26

Intro

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OpenFold - Lessons and Insights From Rebuilding and Retraining AlphaFold2

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  1. 1 Intro
  2. 2 The basic problem
  3. 3 A larger set of problems
  4. 4 Reinventing the space
  5. 5 Summary
  6. 6 Calibration
  7. 7 Questions
  8. 8 Motivations
  9. 9 Complex prediction
  10. 10 Applications
  11. 11 Protein Complex Prediction
  12. 12 Modularity
  13. 13 Outliers
  14. 14 Inverse characteristics
  15. 15 Decals
  16. 16 Convergence characteristics
  17. 17 Fine tuning
  18. 18 Selfassessment
  19. 19 Learning secondary structure elements
  20. 20 Multiscale learning
  21. 21 Learning spatial dimensions
  22. 22 Learning PCA projections
  23. 23 Learning PCA projections independently
  24. 24 How well does a model generalize
  25. 25 Protein fault families
  26. 26 Local vs global aspects

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