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Online Course

Biochemistry: Biomolecules, Methods, and Mechanisms

Massachusetts Institute of Technology via edX

(18)
583
  • Provider edX
  • Cost Free Online Course (Audit)
  • Session In progress
  • Language English
  • Certificate $150 Certificate Available
  • Effort 3-6 hours a week
  • Duration 12 weeks long
  • Learn more about MOOCs

Taken this course? Share your experience with other students. Write review

Overview

Do you want to prepare for medical school, study a STEM field, become a research scientist, or transition to a career in the booming biotechnology industry? Or maybe you just want to understand the chemical reactions that govern life itself. Join Professor Yaffe, an MIT professor and practicing surgeon, as he guides you through the science that inspires countless doctors, researchers, and students alike.

We developed 7.05x Biochemistry with an emphasis on:

  • Developing your scientific thinking skills including articulating hypotheses, performing thought experiments, interpreting data, and designing experiments.
  • Using data based on real scientific experiments and highlighting the scientific process.
  • Asserting that biology is an active field that changes daily through examples of MIT (and other current) research, not static information in a textbook.
  • Visualizing real molecular structures with PyMOL to better understand function and mechanism.
  • Appreciating the quantitative aspects of biochemistry and practicing this quantitation with MATLAB.
  • Translating topics in biochemistry to diseases and medicine.
  • Conveying the authentic MIT firehose experience.
  • Implementing the science of learning in the course design.

We offer a thorough and robust means of certifying edX learners in their mastery of the MITx biochemistry content, through the MITx 7.05x Biochemistry Competency Exam. This challenging option is available only to those who register for the verified-certificate track, and successful completion of this exam is the majority of the assessment grade that counts toward a certificate. The Competency Exam will be open from June 23, 2020 to June 30, 2020.

Syllabus

The course includes the following learning sequences:

  • Introduction to Biochemistry; pH and Buffers
  • Amino Acids and Proteins
  • Protein Purification
  • Protein Structure
  • Protein Folding
  • Hemoglobin and Allostery
  • Hemoglobin and the Bohr Effect
  • Enzyme Chemistry
  • Enzyme as Catalysts
  • Enzyme Kinetics
  • Membranes, Channels, Transporters, and Pumps
  • Blood Clotting
  • Signal Transduction

Taught by

Michael Yaffe, Mary Ellen Wiltrout, Darcy Gordon and Monika Avello

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Reviews for edX's Biochemistry: Biomolecules, Methods, and Mechanisms Based on 18 reviews

  • 5 stars 44%
  • 4 stars 33%
  • 3 stars 17%
  • 2 star 0%
  • 1 star 6%

Did you take this course? Share your experience with other students.

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  • 1
Anonymous
Anonymous is taking this course right now.
This is a fitting addition to the edX/MIT biology offerings (including 7.00x and the 3 7.28x courses). It is extremely comprehensive with respect to both the lectures and the testing, but one thing is always certain in these courses: if you dedicate the amount of time required, which will vary widely...
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Anonymous
Anonymous is taking this course right now.
I am 2/3 through this course and am thoroughly enjoying it. The lecture content is presented by Professor Yaffe in a clear and easy to follow format. The interspersed 'test yourself questions' break up the lectures nicely and help make sure I have understood topics before moving on. The problem sets are written in a fun, anecdotal way that is very engaging and helps me imagine what it would be like attending labs with students. The problem sets are not a simple regurgitation of facts, but challenge you to think critically and truly test understanding of the material. I am concurrently studying to write the MCAT and am finding the knowledge I'm learning here is definitely improving my practice testing in the Bio/Biochem section. Thanks for the opportunity!
Was this review helpful to you? Yes
Bl C
Bl is taking this course right now.
The course overall has good coverage of the subject and engaging supplementary materials through PyMOL, MATLAB, and database usage, but the interface, assessments, discussion environment seem half-baked. Content-wise the lectures are very informative at a good pace. Prof. Yaffe discusses the topics...
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Anonymous
Anonymous is taking this course right now.
First, the bad news: gotta agree with the MATLAB comments. Longest so-called "help" video is less than 4 minutes and even less useful. It's become a guessing game and I'm not going to keep playing it. Feedback/question answers are not timely, and typically not particularly helpful in deciphering....
Was this review helpful to you? Yes
Anonymous
Anonymous is taking this course right now.
This is one of the most challenging courses I've taken - but it has bar-none the best problem sets of any online course I've ever attempted. The problem sets build knowledge while you work through them, in a logical way. It's been a long time since high-school chemistry and algebra, but I've been able to catch up and enjoy the motivation to work through some of those topics again. I think I'm understanding this material much, much better than I did back then! Professor Yaffe is amazing and his love of learning is clear in this course. The first lecture was incredibly tough but that's mainly due to my lack of prerequisites/preparation beforehand. Don't give up there; it does get easier and passing the course is attainable (and a real accomplishment).
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Anonymous
Anonymous is taking this course right now.
I started this course after taking already MITx-7.00x and MITx-7.28 1-3x and to see whether/how this course fills gaps between the other two excellent course . I appreciate the mixture of chalkboard lectures, animations, and test yourself questions. In particular, I like the introduction to PyMOL and MATLAB.

The problem sets with the characters and storyline comes close to real life situations in the lab and are challenging but doable at the same time.
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Anonymous
Anonymous is taking this course right now.
God MATLAB is so frustrating when you do not come from a MATLAB using background. They really should note that this is NEEDED to complete various parts of the course. I will be unenrolling as I have no idea how to do ANYTHING in MATLAB and this course is really putting me off for any further Edx courses.
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Anonymous
Anonymous is taking this course right now.
It doesnt do a good job of explaining Matlab if you are new to it. Dont take the course unless you are very comfortable with Matlab and programming in general. Since this aspect is not explained anywhere, it makes the course frustrating as you ABSOLUTELY use it to finish up graded portions. Would not have taken the course if they highlighted that MATLAB is REQUIRED
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Anonymous
Anonymous is taking this course right now.
MITx biochemistry is an excellent course, and professor Yaffe is an excellent lecturer. All parts of the course are open for audit track, including the problem sets. One drawback is that you need to know Matlab for some questions on the problem sets.
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Anonymous
Anonymous is taking this course right now.
This course provides a great introduction to biochemistry, which can be followed even without prior organic chemistry knowledge. There are some MATLAB coding components though, which may be a bit tricky if you haven't used the language before.
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Kareem S
Kareem is taking this course right now.
The Basics that every biochemist needs. But you need to take your time reviewing the materials, and have a good understanding of the referred chemistry subjects.

I did not finished it, so definitely going to take the re-run.
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Anonymous
Anonymous is taking this course right now.
The course is definitely challenging but you get great feedback on work. I would go in with some knowledge of MATLAB though, its not really explained well in the course.
Was this review helpful to you? Yes
Anonymous
Anonymous is taking this course right now.
I am 2/3 through this course, and had only planned on browsing through some of the content, but it is presented in such an interesting way that it really got me hooked on to biochemistry. The presentation of the material is great, the length of videos and the intermediary test yourself questions are all spaced appropriately, so that the learner remains engaged in the course through out. It is also motivating to see yourself progress. Overall, I feel that I have already gained a better foundational knowledge of biochemistry and am motivated to learn more about various subjects in the field that interest me. Am extremely grateful to live in a time when such content is freely available.
Was this review helpful to you? Yes
Anonymous
Anonymous is taking this course right now.
It is super hard if you are an above-average student, but it challenges you to get into a very different league of understanding the concepts of Biochemistry. I personally believe that it brought me out of my comfort zone and has already helped me immensely in my PhD research as I work with proteins. I'd highly recommend this course to anyone who is currently pursuing research in any area related to biochemistry plus has a keen interest to level up their career. I hope I could receive the Verified Certificate, as it is proof that you are a lifelong learner and it adds some weightage on your CV if you have a degree already and/or are in a scientific field.
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Anonymous
Anonymous is taking this course right now.
The course is difficult. I do not think it is an intermediate course, even though I have previous knowledge of some of the topics,although I am studying at a Greek University that has a similar content with the course. Moreover, the professor recalls meanings from other courses that the students of MIT have already done and many of them I did not know them.Last but not least, they have this MATLAB program, that they do not explain really well and they do not do a good work. As a result,I am having a really harsh time in answering many questions that require this program.
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Anonymous
Anonymous is taking this course right now.
This is a fantastic course. Thanks to everybody for making it available. You may need to review the lectures and make your own research and experiments in order to achieve a good understanding. I hope I can complete this course, otherwise I will take it again on the next run. Not only the lectures, but also the exercises are very interesting. The exercises are not only validating your knowledge. Thanks to the exercises you learn and understand things not covered by the lectures.
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Anonymous
Anonymous is taking this course right now.
The content is a fascinating look at how biological systems are formed and regulated.

Lectures are well executed and build upon each other.

Learning questions reinforce lectures.

PDF handouts are helpful in review and problem sets.

Problem sets are interesting and help to apply and reinforce learning without being too tricky.

The problem set due date schedule was too aggressive considering that not everyone starts the class at the same time.

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Anonymous
Anonymous is taking this course right now.
Thank you. but I can¨t with Matlab and Pymol. There is a lot of work it´s very very interesting I have learned many things .
Was this review helpful to you? Yes
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