The lectures are really great, and Eric Lander is knowledgeable and engaging, but there is a disconnect between what it taught and what is tested on. It seems like what is taught is very generalized, but the problem sets and exams are exceedingly detailed and nitty gritty, and much of the time it feels as if youre being tested more on nomenclature than concepts.
I would not recommend this to anyone who doesnt already have a pretty large base of scientific knowledge (both chemistry and biology). Although its classified as a beginner course, requiring no prerequisites, in order to be successful, you need to already know your stuff.
All that said, Lander's commentary on the discovery of things now held to be scientific facts is to die for. Its very informative, and he teaches a useful critical mindset. I dont regret taking the course, even though its seriously stressing me out.