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Molecular Biology - Part 1: DNA Replication and Repair

Massachusetts Institute of Technology via edX

13 Reviews 810 students interested
  • Provider edX
  • Subject Biology
  • Cost Free Online Course (Audit)
  • Session Self Paced
  • Language English
  • Certificate $99 Certificate Available
  • Effort 4-6 hours a week
  • Start Date
  • Duration 8 weeks long
  • Learn more about MOOCs

Taken this course? Share your experience with other students. Write review

Overview

You’re acquainted with your DNA, but did you know that your cells synthesize enough DNA during your lifetime to stretch a lightyear in length? How does the cellular machinery accomplish such a feat without making more mistakes than you can survive? Why isn’t the incidence of cancer even higher than it is? And, if the DNA in each and every cell is two meters long, how is this genetic material compacted to fit inside the cell nucleus without becoming a tangled mess?

Are you ready to go beyond the “what" of scientific information presented in textbooks and explore how scientists deduce the details of these molecular models?

Take a behind-the-scenes look at modern molecular genetics, from the classic experimental events that identified the proteins involved in DNA replication and repair to cutting-edge assays that apply the power of genome sequencing. Do you feel confident in your ability to design molecular biology experiments and interpret data from them? We've designed the problems in this course to build your experimental design and data analysis skills.

Let’s explore the limits of our current knowledge about the replication machinery and pathways that protect the fidelity of DNA synthesis. If you are up for the challenge, join us in 7.28x Part 1: DNA Replication and Repair.

Follow the latest news from MITx Biology @MITxBio on Twitter.

Taught by

Tania A. Baker and Stephen P. Bell

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Reviews for edX's Molecular Biology - Part 1: DNA Replication and Repair
4.7 Based on 13 reviews

  • 5 stars 69%
  • 4 stars 31%
  • 3 star 0%
  • 2 star 0%
  • 1 star 0%

Did you take this course? Share your experience with other students.

Write a review
  • 1
Maximilian V
5.0 4 months ago
Maximilian is taking this course right now, spending 3 hours a week on it and found the course difficulty to be hard.
To put my review into context:

I hold a MSc in Agricultural sciences, working in (molecular) plant breeding.

That means: I am familiar with genetics and replication, mitosis, meiosis.

This course is of interest for me because I wanted to get behind the molecular mechanisms of all the lab-techniques I use like PCR / Sequencing to possibly improve the assays I develop or to adopt assays.

The course requires quite some attention but it is totally worth it!

It gives so much understanding on how the molecular machinery works in concert and everything is backed-up with experiments. Sometimes WAY to detailed (for me) but overall a great course.

I especially like the explanatory videos.

Really well done!

Was this review helpful to you? Yes
Anonymous
5.0 5 months ago
Anonymous completed this course.
Very intense but extremely interesting! I loved the way not only the cool parts about the biological mechanisms were taught, but also all the assays to find out about these mechanisms. Biology has a lot of logic and I liked this clean aspect of it that MIT reveals. I'm excited for Part 2!

- Just one small remark: why can't all 3 Parts of Molecular Biology be open all the time (or most) like with 7.00x? I would have liked to continue on instead of waiting for the next part to open... (unless the course is new and I just haven't realised) :)
Was this review helpful to you? Yes
Anonymous
5.0 3 months ago
Anonymous is taking this course right now.
Being a biology major, this course is helping me a lot regarding understanding the molecular mechanisms involved in events happening in the cell nucleus or with bacterial DNA. The better part is the exposures to different assays used in different labs. This creates a proper conceptual understanding of the assay techniques and how to troubleshoot them. Thus it is great for both theoretical studies and for being a researcher.
Was this review helpful to you? Yes
Richard S
5.0 2 months ago
Richard is taking this course right now.
This course is wonderful for me. I took the MIT edX Intro Biology course, and found the lesson plan, homework and quizzes to be optimized for learning. Continuing my biology studies here has kept up the rigor in a way that really seems to trick my brain into understanding. MIT's professors really do a great job of making the subject interesting.
Was this review helpful to you? Yes
Anonymous
4.0 6 days ago
Anonymous is taking this course right now.
This is a very good course. I withheld a star because I feel certain subjects need to be clarified more as they are explained, especially the assays. The devil is in the details when it comes to assays and every assumption needs to be made clear. Animations would be quite helpful to detail the steps in Assays. As with many online courses, quiz questions sometimes seem too vaguely described and seem to incorporate assumptions in the mind of the question designer that are not explicit and leave too much ambiguity. Some questions are very well formulated. The lecturer is great, holds your a…
Was this review helpful to you? Yes
Maria A
5.0 3 months ago
Maria is taking this course right now, spending 3 hours a week on it and found the course difficulty to be medium.
It is a must sought course for those with a background in Biotechnology or other Life Sciences. Very informative and thought-provoking course.
Was this review helpful to you? Yes
Anonymous
5.0 4 months ago
Anonymous completed this course.
I Agree, it was intense and extremely interesting! I have to say that it wasn't easy for myself, especially as a non-native speaker person. Sometimes a passive voice produced a tricky things with the question.

I complitely agree that having a full-lenght cource would be much more intrestingly.

I'm also have to propose the idea personal message to course instructor due to the reason of privat answers.

Thank you once more for knowledge,experience and challenge.

Serg.
Was this review helpful to you? Yes
Anonymous
4.0 2 months ago
Anonymous completed this course.
I just want to request one thing. Please, add videos for experimental assays also. Education in my place is shit. I am a zoology majo(almost completed) and I have never even seen the gel used in electrophoresis , I can't explain how left out I felt when I saw Professors Bell saying to students that you all have worked with endo/exo-nucleases and gels.

At least people like me will be able to see what experiments look like in real life. Please!
Was this review helpful to you? Yes
Anonymous
4.0 3 months ago
Anonymous is taking this course right now.
This class has been interesting, informative and user friendly. There are a good amount of well designed questions to test your knowledge as you go along as well as quizzes to help solidify your knowledge. Both the test yourself questions and the quizzes allow you to see the answers after you have finished which is very helpful in understanding more precisely where your knowledge gaps are.
Was this review helpful to you? Yes
Anonymous
4.0 3 months ago
Anonymous completed this course.
I liked learning about the different assays, which will be really helpful in research carrier. Although I would have liked more of detailed mechanisms of Double strand break repair, especially for eukaryotic cases. Overall it was a great experience learning different molecular mechanisms, assays involved in finding new factors, and troubleshooting different problems which happen in lab.
Was this review helpful to you? Yes
Anonymous
5.0 a week ago
Anonymous is taking this course right now.
The course is worth it and it needs focus and time. Illustrations makes it easy to understand, however in order to understand more reading and at least watching the videos twice might have. The only worry is that the course is too long
Was this review helpful to you? Yes
Hamilton B
5.0 4 months ago
Hamilton completed this course, spending 5 hours a week on it and found the course difficulty to be medium.
I am a practicing MD PhD and reviewing and updating my genetic knowledge. The information is available in textbooks but I also enjoy the quizzes and the ability to ask questions.
Was this review helpful to you? Yes
Anonymous
5.0 4 months ago
Anonymous is taking this course right now.
Pretty good. The teacher gets boring sometimes but most of the time he's interesting. The animations make it easier to understand, The Quizzes are fun, but quite hard!
Was this review helpful to you? Yes
  • 1

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