The first part covers buffer overflows and related memory attacks. Buffer overflows are really well explained, but the quiz and programming project can be difficult if you don't know C.
Next there was a section on web security, like SQL injection, XSS and CSRF. Again, very well explained. The programming project consisted of trying to break into a web site - great fun!
The final block covered static analysis, symbolic execution, fuzzing and penetration testing.
All in all a very enjoyable course, not least because profressor Hicks is very pedagogical - one of the best lecturers I have encountered in MOOCs. The quizzes are relatively easy, but the first and second programming projects took a bit of effort to complete. However, the workload was quite a bit less than for other programming courses I have taken on Coursera.
I've written a more detailed review here: http://henrikwarne.com/2015/10/20/coursera-course-review-software-security/