This course focuses on the development of mRNA for therapy, with an emphasis on in vitro-transcribed mRNA for protein therapy. The learning outcomes include understanding RNA-mediated mechanisms, investigating RNA-mediated immune activation, and exploring the therapeutic potentials of mRNA. The course covers topics such as mRNA structure, delivery methods, double-stranded mRNA, and the application of nucleoside-modified RNA. The teaching method includes presentations and discussions led by industry experts. This course is intended for individuals interested in mRNA technology, protein therapy, and the development of nucleoside-modified mRNA for therapeutic purposes.
Overview
Syllabus
Introduction
Welcome
Presentation
Milestones
mRNA Structure
mRNA Delivery
Doublestranded mRNA
Synchronized mRNA
Lipofacting mRNA
mRNA delivery to mammalian cells
cardiology
nitric oxide
met Drew Weissman
mRNA Therapy
Taught by
AAAS Annual Meeting