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University of Malaya

Advanced Research Techniques in Parasitology

University of Malaya via FutureLearn

Overview

Add new research methods to your toolkit

On this six-week course taught by expert researchers at the Universiti of Malaya, you’ll master new and cutting-edge research methods in parasitology.

From molecular diagnostics to genetic manipulation and spatial-temporal analysis, you’ll be armed with a toolbox of techniques for your next research project.

Take a deep dive into molecular diagnostics, in vitro blood-stage cultures, and genetic manipulation

After reviewing standard methodology and basic concepts in parasitology research, you’ll delve further into specific techniques and methods.

You’ll learn about the latest developments in molecular diagnostics, in vitro blood-stage culture analysis, and genetic manipulation, gaining practical guidance on applying the methods in your own research.

Learn how to build a successful immunology research project

In the third week of the course, you’ll master the art of experiment design and execution, focusing specifically on immunology research.

You’ll compare a range of existing research projects, examining whether and how they meet their research objectives.

Discuss how spatial-temporal factors could influence your project

The course will conclude by investigating the role of spatial-temporal analysis in tropical disease research. You’ll gain an introduction to Geographical Information Systems, and reflect on how this data could inform experiment design.

By the end of the course, you’ll have the skills and knowledge you need to plan your next parasitology research project.

This course is designed for anyone interested in parasitology. Having a foundation in parasitology or microbiology can enhance comprehension of the material, but it is not mandatory. It will be particularly valuable to students pursuing or interested in pursuing a master’s degree in the field.

Syllabus

  • Introduction to advanced research techniques
    • Getting Started
    • Advanced research techniques
    • Weekly wrap up
  • Molecular diagnostics: a revolution in progress
    • Introduction to Molecular diagnostics
    • Polymerase Chain Reaction
    • Droplet Digital PCR
    • Loop-Mediated Isothermal Amplification Method
    • Weekly Wrap up
  • How to put together a good Immunology research?
    • Background & Introduction
    • Experiment designing
    • Execution
    • Weekly Wrap up
  • Plasmodium in vitro blood-stage culture: what are we missing?
    • Plasmodium in vitro blood-stage culture: what are we missing?
    • Variation of in vitro Plasmodium culture
    • What do you need to start Plasmodium culture?
    • Obstacles in in vitro Plasmodium culture
    • Weekly Wrap up
  • Genetic manipulation in parasitology: not just cut and pasted!
    • What is CRISPR-Cas9?
    • How CRISPR-Cas9 works
    • CRISPR-Cas9 in Plasmodium sp.
    • CRISPR-Cas9 in other parasites and vectors
    • Weekly Wrap up
  • Spatial-temporal analysis in tropical diseases: its application for decision-making
    • Introduction to Geographic Information System (GIS)
    • What is a spatial data model?
    • What is spatial data analysis?
    • How is GIS used in disease control and planning?
    • Weekly wrap

Taught by

Yee Ling Lau

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