Students who complete this class will understand that analytical instruments are not black boxes, but rather complex tools whose utility depends in detail on how analysts both configure and apply them. Towards that end there are three pimary objectives. First, students will learn facts about major classes of instruments commonly used in chemical analysis. Their knowledge will be captured by the ability to block diagram these complex pieces of equipment, and tailor the specifications to the measurement needs. Second, the course will cover the basics of instrumental calibration and quality control. Analysts will develop the ability to apply calibration curves, internal standards and the method of standard addition as needed for various measurement problems. Finally, students must learn how to select and tailor the best instrumental method given a particular measurement need. This higher level skill involves critical evaluation of the strengths and limitations of the various method, and the ability to understand the context behind a measurement need.