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Medical Biomaterials

Indian Institute of Technology Madras via NPTEL

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Overview

Biomaterial is any natural or synthetic material used to replace or augment a part of the body so that it improves the human health by restoring the function of the natural living tissue or organ. It should be biocompatible and should not cause any adverse systemic reaction to the host. It could be a polymer,metal,ceramic or combination of these. It may have to be in contact or remain in the body for few hours or for rest of the life of the person.

Syllabus

 

Week  1

Introduction to Biomaterials

 

Background history

 

History

 

Properties (Mechanical and Physico-chemical)

 

Properties (Mechanical and Physico-chemical)

Week  2

Mechanical properties

 

Mechanical properties

 

Resorbability, biodegradation

 

Resorbability, biodegradation

 

Biofilm

Week  3

Biofilm

 

Biofilm

 

Biofilm

 

Material characterization - Analytical instruments

 

Analytical instruments

Week  4

Analytical instruments

 

Analytical instruments

 

Biological responses, compatibility, cytotoxicity

 

Proteins, Tissue and blood Response

 

Cell-biomaterial interaction

Week  5

Animal trials (in vivo)

 

Animal trials

 

Metals-types, classifications, applications

 

Metals -  properties

 

Metals -  properties

Week  6

Metals -  properties

 

Metals

 

Polymers-types, classifications, applications

 

Polymers

 

Polymers

Week  7

Blends/composites

 

Biopolymers

 

Hydrogels

 

Preparation of different morphologies (with experiments)

 

Surface modifications (with experiments)

Week  8

Ceramics 

 

Drug delivery systems/encapsulation

 

Biomaterials for cardiovascular/pulmonary/ophthalmological applications

 

Biomaterials for urinary/dental/skin applications

 

Sterilization of implants, device failures, unique issues, conclusion

 

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