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University of California, Los Angeles

Modern Radiation Therapy Techniques in the Treatment of Esophageal Cancer - Ann C. Raldow, MD, MPH

University of California, Los Angeles via YouTube

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Overview

This course on modern radiation therapy techniques in the treatment of esophageal cancer aims to educate learners on the role of radiation therapy in treating esophageal cancer, types of radiation therapy used, treatment processes, and common side effects. The course covers topics such as the impact of DNA damage, fractionation, dose constraints, and recent research studies in the field. The teaching method includes lectures, case studies, and discussions. This course is intended for radiation oncologists, oncology nurses, medical students, and healthcare professionals involved in the treatment of esophageal cancer.

Syllabus

Intro
Disclosures
Esophageal Cancer Outline
Epidemiology
Risk Factors
Anatomy
Clinical Presentation
Workup
Treatment Paradigm
What is Radiation Therapy?
How Does Radiation Kill Cancer Cells?
Impact of DNA Damage
How do the normal cells survive?
Fractionation
External Beam Radiation Therapy
Simulation
Dose Constraints
Esophageal Cancer Timeline
Van Hagen, CROSS
A Randomized Phase III Trial on the Role of Esophagectomy in Complete Responders to Preoperative Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESOPRESSO) (Park, Anticancer Res. 2019)
ESOPRESSO (Park, Anticancer Res. 2019)
Disease-free survival, progression-free survival, time to progression, and overall survival according to treatment arm
A multi-center, randomized, prospective study evaluating the optimal radiation dose of definitive concurrent chemoradiation for inoperable esophageal squamous cell carcinoma (Xu, ASCO 2018)
A randomized controlled phase Ill multicenter study on dose escalation in definitive chemoradiation for patients with locally advanced esophageal cancer: ARTDECO study (Hulshof, GIASCO 2020)
Conclusion

Taught by

UCLA Health

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