Modern Radiation Therapy Techniques in the Treatment of Esophageal Cancer - Ann C. Raldow, MD, MPH

Modern Radiation Therapy Techniques in the Treatment of Esophageal Cancer - Ann C. Raldow, MD, MPH

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Intro

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1 of 25

Intro

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Modern Radiation Therapy Techniques in the Treatment of Esophageal Cancer - Ann C. Raldow, MD, MPH

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  1. 1 Intro
  2. 2 Disclosures
  3. 3 Esophageal Cancer Outline
  4. 4 Epidemiology
  5. 5 Risk Factors
  6. 6 Anatomy
  7. 7 Clinical Presentation
  8. 8 Workup
  9. 9 Treatment Paradigm
  10. 10 What is Radiation Therapy?
  11. 11 How Does Radiation Kill Cancer Cells?
  12. 12 Impact of DNA Damage
  13. 13 How do the normal cells survive?
  14. 14 Fractionation
  15. 15 External Beam Radiation Therapy
  16. 16 Simulation
  17. 17 Dose Constraints
  18. 18 Esophageal Cancer Timeline
  19. 19 Van Hagen, CROSS
  20. 20 A Randomized Phase III Trial on the Role of Esophagectomy in Complete Responders to Preoperative Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESOPRESSO) (Park, Anticancer Res. 2019)
  21. 21 ESOPRESSO (Park, Anticancer Res. 2019)
  22. 22 Disease-free survival, progression-free survival, time to progression, and overall survival according to treatment arm
  23. 23 A multi-center, randomized, prospective study evaluating the optimal radiation dose of definitive concurrent chemoradiation for inoperable esophageal squamous cell carcinoma (Xu, ASCO 2018)
  24. 24 A randomized controlled phase Ill multicenter study on dose escalation in definitive chemoradiation for patients with locally advanced esophageal cancer: ARTDECO study (Hulshof, GIASCO 2020)
  25. 25 Conclusion

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