This course follows on from Data Mining with Weka and More Data Mining with Weka. It provides a deeper account of specialized data mining tools and techniques. Again the emphasis is on principles and practical data mining using Weka, rather than mathematical theory or advanced details of particular algorithms. Students will analyse time series data, mine data streams, use Weka to access other data mining packages including the popular R statistical computing language, script Weka in Python, and deploy it within a cluster computing framework. The course also includes case studies of applications such as classifying tweets, functional MRI data, image classification, and signal peptide prediction.