This is one of the three classes from Duke that's worth taking -- avoid the Bayesian course, which is the fourth one in their sequence. I believe this course is the third.
The course is largely talking-head-with-slides. I recommend taking the quizzes almost right away (you'll fail, but you'll get some story problems to solve). Then work through the lectures, reading, and homework, and you should have little problem with the quizzes.
I applied myself hard to the materials and got a lot out of it. The course final is a project where you use RStudio (which you'll use in all of the courses of this sequence) to build a web page of data analysis. This is nice because it gives you portfolio material.