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Indian Institute of Technology Madras

Medical Biomaterials

Indian Institute of Technology Madras and NPTEL via Swayam

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Biomaterial is any natural or synthetic material used to replace or augment a part of the body so that it improves the human health by restoring the function of the natural living tissue or organ. It should be biocompatible and should not cause any adverse systemic reaction to the host. It could be a polymer,metal,ceramic or combination of these. It may have to be in contact or remain in the body for few hours or for rest of the life of the person.INTENDED AUDIENCE : UG/PG Biotech programmes (core or elective) and research scientists in biotechnology, material science and metallurgy,surgeons,clinicians, dentists.PREREQUISITES : Basics of physics,chemistry and mathematics.INDUSTRY SUPPORT : Implants,devices,biomaterials industries.


Week 1: Introduction to Biomaterials
Background history
Properties (Mechanical and Physico-chemical)
Properties (Mechanical and Physico-chemical)

Week 2: Mechanical properties
Mechanical properties
Resorbability, biodegradation
Resorbability, biodegradation

Week 3: Biofilm
Material characterization - Analytical instruments
Analytical instruments

Week 4: Analytical instruments
Analytical instruments
Biological responses, compatibility, cytotoxicity
Proteins, Tissue and blood Response
Cell-biomaterial interaction

Week 5: Animal trials (in vivo)
Animal trials
Metals-types, classifications, applications
Metals - properties
Metals - properties

Week 6: Metals - properties
Polymers-types, classifications, applications

Week 7: Blends/composites
Preparation of different morphologies (with experiments)
Surface modifications (with experiments)

Week 8: Ceramics
Drug delivery systems/encapsulation
Biomaterials for cardiovascular/pulmonary/ophthalmological applications
Biomaterials for urinary/dental/skin applications
Sterilization of implants, device failures, unique issues, conclusion



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