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New Biochemical Clues in Cell Receptors Help Explain How SARS-CoV-2 Hijacks Cells - AAAS Annual Meeting

AAAS Annual Meeting via YouTube

Overview

This course explores new biochemical insights into how SARS-CoV-2 hijacks human cells by targeting specific sequences within cell receptors. The learning outcomes include understanding the cellular processes exploited by the virus for cell entry, replication, and spread, as well as identifying potential targets for therapeutic interventions. The course teaches skills such as analyzing short linear motifs (SLiMs) in receptors, predicting their roles in cellular processes, and exploring interactions between SLiMs and proteins involved in endocytosis and autophagy. The teaching method involves presentations, molecular tests, and discussions. The intended audience includes researchers, scientists, healthcare professionals, and individuals interested in the biochemistry of viral infections.

Syllabus

Introduction
Welcome
Overview of the Life Cycle
Early Model
Evolutionary Signals
New Linear Motifs
How Does SARSCoV2 Work
Conclusion
Questions
Presentation
Background
Fluorescent Polarization
Cterminus
Cterminal PTZ Binding Motif
Overlapping Binding Motif
Lyr Binding Motif
Summary
Questions and Answers
Closing Thoughts

Taught by

AAAS Annual Meeting

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