This course covers the fundamentals of genetics, including Mendelian genetics, chromosomal theory of inheritance, eukaryotic genome organization, bacterial transformation, conjugation, transposons, gene mapping, and pedigree analysis. By the end of the course, students will be able to understand genetic principles, solve genetics problems, and analyze family pedigrees. The course teaches skills such as genetic problem-solving, pedigree chart interpretation, and understanding the mechanisms of genetic inheritance. The teaching method includes lectures, animations, and problem-solving exercises. This course is intended for students and professionals interested in gaining a comprehensive understanding of genetics and its applications.
Overview
Syllabus
Mendel and genetics.
Mendelian genetics 1.
Mendelian genetics 2.
Mendelian genetics 3.
Chromosomal basis of inheritance 1.
Chromosomal theory of inheritance 2.
Chromosomal theory of inheritance 3.
Eukaryotic genome organization 1 | chromosome, nucleosome.
Eukaryotic genome organization 2 | chromosome, nucleosome.
Mechanism of competence generation.
Griffith experiment | bacterial transformation experiment.
DNA transformation in bacteria.
Conjugation in bacteria.
Bacterial conjugation.
conjugation between f + and f bacteria animation.
Self transmissible plasmid conjugation.
F plasmid | F+ F- F prime and hfr.
Conjugation between hfr and f bacteria.
Conjugation between F+ & F bacteria.
Bacterial Transformation experiment.
Uptake of DNA during transformation | natural competence.
Composite and noncomposite transposons.
Activator transposable elements.
Ds and Ac transposable elements.
IS elements.
Role of transposition in bacterial cells.
Transposition of IS elements.
Cut and paste DNA transposition.
Different mechanisms of transposition.
Genetic organization of LINE and SINE.
Mechanism of transposition of retroviral transposons.
Transposons overview.
Types of transposons.
Transposition of a poly A retrotransposon.
Gene mapping in E.coli.
Genetics problems 7 (lethal gene).
Genetics problems 6 (Codominance).
Genetics problems 4 (incomplete dominance).
Genetics problems 3 (incomplete dominance).
Genetics problems 1 (introduction).
Genetics problems 2 (dihybrid cross).
Pedigree analysis- sex linked recessive pedigree.
Pedigree analysis- sex linked dominant pedigree.
Pedigree analysis - autosomal recessive.
Pedigree analysis- autosomal dominant.
Pedigree chart.
Pedigree analysis - understanding family tree 1.
Pedigree analysis - understanding family tree 2.
Taught by
Shomu"s Biology
