Fundamentals of central dogma, Part 1. Fundamentals of central dogma, Part 2. Fundamentals of central dogma, Part 3. Chromosome Structure and Function. Pedigree Analysis. Complications in Mendelian Pedigree Patterns. DNA Cloning and Hybridization Techniques - Part 1. DNA Cloning and Hybridization Techniques - Part 2. Practice Session 1: Problems Related to Pedigree Analysis. Practice Session 2: Restriction Fragment Length Polymorphism and its Applications. Mutations and instability of human DNA (Part 1). Mutations and instability of human DNA (Part 2). Animal Models for Human Diseases. Positional cloning of genes for monogenic disorders. Human Genome Project and HapMap project.
The development of genomic tools and data sets has transformed the nature of medical discovery, enabling scientists to undertake comprehensive and powerful explorations rather than being confined to testing hypotheses focused on candidate pathways. With the completion of the first reference sequence of the human genome,3 attention shifted from searching for genes to discovering their functions.