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Overview
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This course explores the significance of the Krebs cycle in powering life and death, challenging the traditional view of biology dominated by genes. The learning outcomes include understanding the metabolic pathways of life, the efficiency of the Krebs cycle, and its role in diseases like cancer. The course covers topics such as cellular respiration, bioinformatics, photosynthesis, and the interconnectedness of life on Earth. The teaching method involves a lecture format with insights from scientific research and historical discoveries. The intended audience includes individuals interested in biology, biochemistry, and the origins of life.
Syllabus
Metabolic pathways of life
The Krebs cycle - simplified
How cells respire
What cancer taught us about the Krebs cycle
How is the Krebs cycle efficient?
The reverse Krebs cycle
Margaret Dayhoff - the founder of bioinformatics
Discovering alkaline hydrothermal vents
The need for genes
Supercharging the earth's battery through photosynthesis
Rise of the predators
The Krebs cycle in disease
Taught by
The Royal Institution