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How to Clone a Mammoth - The Science of De-Extinction - With Beth Shapiro

The Royal Institution via YouTube

Overview

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This course explores the science of de-extinction, focusing on the possibility of bringing back extinct species like mammoths and passenger pigeons. The learning outcomes include understanding the process of de-extinction, from selecting species for restoration to sequencing genomes and managing revived populations. The course covers topics such as ancient DNA, genetic diversity, somatic cell nuclear transfer, and CRISPR technology. The teaching method involves lectures by an evolutionary biologist and discussions on the feasibility and implications of de-extinction projects. The intended audience includes individuals interested in genetics, evolutionary biology, and conservation science.

Syllabus

Intro
Climate change
Rapid global warming
Ancient DNA
Genetic Diversity
DeExtinction
Mammoths
Somatic Cell Nuclear Transfer
WellPreserved Mammoths
Mammoth Genomes
Human Genome
Shotgun Sequencing
Mammoth Sequencing
Plan C
CRISPR Caste 9
What should we target
What else
Whats next
Feasibility of Phase 2
Stellers Sea Cow
We are much more than genomes
Differences in appearance
Mammoth deextinction
Deextinction projects
Ecological reasons
Impact of herbivores
Impact of elephants
Black footed ferrets

Taught by

The Royal Institution

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