Human Leucocyte Antigens and Their Applications - Professor Alejandro Madrigal

This course aims to educate learners on the importance of Human Leucocyte Antigens (HLA) in unrelated donor transplantation and the treatment of malignant haematological conditions using modified Lymphocytes. The course covers topics such as the polymorphism of HLA, donor selection, and the use of novel methods like Adoptive Cell therapy. Learners will acquire knowledge on HLA testing, matching, and the implementation of advanced therapies like CAR-T and NK cells. The teaching method includes lectures on the immune system, HLA structure, third-generation sequencing, stem cell transplantation, and the application of viral vectors in cell therapy. This course is intended for healthcare professionals, researchers, and individuals interested in understanding the role of HLA in transplantation and cell-based therapies for malignant disorders.