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The course teaches how to manage Python dependencies effectively using the pyproject.toml file specification and tools like Poetry, Hatch, Pipenv, and pip-tools. Participants will learn to simplify dependency installation, understand the importance of dependency resolution, and utilize pipx for isolating Python tools. The teaching method is a 29-minute talk from the EuroPython Conference 2019. This course is intended for Python developers looking to enhance their dependency management skills.