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Overview
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This course explores the cell programming revolution, focusing on reprogramming cells at the genetic level to access the entire operating system of life. The learning outcomes include understanding the importance of cell reprogramming, gene targeting approaches, and the deterministic induction of new cellular identities. The course teaches skills such as programming biology, gene regulatory networks, and engineering biology. The teaching method involves a lecture by Dr. Mark Kotter, a neurosurgeon and stem cell biologist, with insights from his research and entrepreneurial endeavors. The intended audience includes individuals interested in biology, biotechnology, regenerative medicine, and the intersection of science with technology and mathematics.
Syllabus
Intro
Last wave of innovation
Gene regulatory networks
Programming biology
Programming maths
Engineering biology
Programming higher species
Selfmade choices
The new paradigm
Can this paradigm be generalized
Mark Kotters lab
Number of experiments required
Refinement of experimental approach
How is the cell type determined
Harald Weintraub
Human Cell Atlas
Liver cells
Whats next
Leading innovators
Alzheimers
Cell therapies
Future applications
Taught by
The Royal Institution