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Design Principles of Physiological Circuits and Their Aging Process - Uri Alon

Institute for Advanced Study via YouTube

Overview

Explore the intricate design principles of physiological circuits and their aging process in this comprehensive lecture by Uri Alon at the Institute for Advanced Study. Delve into topics such as intrinsic and extrinsic mortality, disease incidence rates, and the mass longevity triangle. Examine the factors influencing lifespan, including gender differences and the optimal timing for antiaging interventions. Investigate the mechanisms of aging, damaged cells, dominance hierarchy, and senescence. Learn about the impact of drugs on the aging process, with a focus on lung senescence and the bystander effect. Gain insights into the Crammers equation and its relevance to aging research. This hour-long talk, part of the Prospects in Theoretical Physics 2019 series, offers a deep dive into the great problems in biology for physicists.

Syllabus

Intro
Intrinsic and Extrinsic Mortality
Incidence Rate of Diseases
Mass Longevity Triangle
Lifespan
Women live longer
When to start antiaging intervention
Aging
Damaged Cells
Dominance Hierarchy
Senescence
Drugs
Age
Lung senescence
The bystander effect
The Crammers equation

Taught by

Institute for Advanced Study

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